Science: 10 Mistakes that Most People Make

What Is Flow Chemistry?

When talking about flow chemistry, this is a chemical reaction that runs in continuous flow stream rather than batch production. To be able to make things a lot simpler, the pumps move the fluid in the tube and when the tube joins in each other, the fluids then make a connection. In case that the fluids are reactive, there will be a spike in reaction.

As a matter of fact, flow chemistry is a technique that’s well known and being used for big scale projects in manufacturing large quantities of the given material. On the other hand, the term has been coined just recently for the application on laboratory scale. More often than not, micro-reactors are put into used.

Continuous reactors are manufactured using non reactive material similar to glass, polymers and stainless steel and typically tube-like. When it comes to the method of mixing, it can be either of the two, static mixers or diffusion. With continuous flow reactors, this is able to make good control on reaction condition that includes the heat transfer, time and mixing.

Residence time for the reagent in the reactor or amount of time wherein the reaction is cooled or heated is checked from the volume of reactor and the flow rate through it. For this reason, in an effort to attain longer residence time, the reagents may be pumped slowly and /or bigger volume reactor is put into used.

The production rates on the other hand will not be constant and it varies from liters per minute to nano-liters per minute.

Few examples of the flow reactors are spinning tube reactors, spinning disk reactors or otherwise called as Colin Ramshaw, oscillatory flow reactors, multi cell flow reactors, microreactors, aspirator reactors and hex reactors. In regards to aspirator reactor, a pump is used to propel one reagent that sucks in the reactant.

Smaller scale of the micro-flow reactors or micro reactors could be perfect for process development experiments. But this doesn’t indicate that flow chemistry isn’t able to operate at bigger scale; synthetic productive benefits from mass transfer, mass transport and even improved thermal.

Processes development is changing from serial approach to parallel. When it comes to batch, the chemist will first work on it which will then be followed by a chemical engineer. Now for flow chemistry, this changes to parallel approach to which both the chemical engineer and the chemist are working side by side. There is usually a plant setup in the lab to which the tool is meant for both. This particular set up may be used either for non commercial or commercial setting.

It’s feasible as well to run experiments in flow chemistry using more complicated techniques like solid phase chemistries while solid phase reagents, scavengers or catalysts may be used in the solution and be pumped through glass columns.

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